Influence of biomechanical characteristics on pain and function outcomes from exercise in medial knee osteoarthritis and varus malalignment: Exploratory analyses from a randomized controlled trial

KL Bennell; F Dobson; EM Roos; ST Skou; P Hodges; TV Wrigley; M Kyriakides; B Metcalf; MA Hunt; RS Hinman

Journal article

Influence of biomechanical characteristics on pain and function outcomes from exercise in medial knee osteoarthritis and varus malalignment: Exploratory analyses from a randomized controlled trial

KL Bennell, F Dobson, EM Roos, ST Skou, P Hodges, TV Wrigley, M Kyriakides, B Metcalf, MA Hunt, RS Hinman

Arthritis Care and Research | Published : 2015

DOI: 10.1002/acr.22558

Abstract

Objective To investigate whether selected biomechanical characteristics influence changes in pain and physical function with exercise in people with medial knee osteoarthritis (OA) and varus malalignment. Methods We conducted post hoc exploratory analyses from a randomized controlled trial involving 100 people with medial knee OA and varus malalignment who were randomly allocated to one of two 12-week exercise programs (quadriceps strengthening [QS] or neuromuscular exercise [NEXA]). The outcome measures were change in overall average knee pain (visual analog scale) and self-reported physical function (Western Ontario and McMaster Universities Osteoarthritis Index). Candidate biomechanical c..

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University of Melbourne Researchers

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Grants

Awarded by National Health and Medical Research Council

Awarded by Australian Research Council Future Fellowship

Funding Acknowledgements

Supported by the National Health and Medical Research Council (grants 628644 and 631717). Drs. Bennell and Hodges's work was supported by National Health and Medical Research Council Fellowships (1058440 and 1002190, respectively). Dr. Hinman's work was supported by an Australian Research Council Future Fellowship (FT130100175).Dr. Bennell has received consulting fees, speaking fees, and/or honoraria (less than $10,000) from Physitrack and receives royalties for an Asics osteoarthritis shoe and an osteoarthritis DVD for physiotherapists. Dr. Hinman receives royalties for an Asics osteoarthritis shoe.